| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
isoform 4), Estrogen Receptor (alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, WB |
| Recommended dilutions: |
Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the Estrogen Receptor antibody (isoform 4) may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Estrogen Receptor antibody (isoform 4)is to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P03372-4 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in several transcript variants, DNA binding, Estrogen and its receptors are essential for sexual development and reproductive function, Estrogen receptors are also involved in pathological processes including breast cancer, The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2, a ligand-activated transcription factor composed of several domains important for hormone binding, and activation of transcription, and osteoporosis, but also play a role in other tissues such as bone, endometrial cancer, which differ in their 5' UTRs and use different promoters, This gene encodes an estrogen receptor |
| Immunogen: |
A portion of amino acids 271-300 from the human protein was used as the immunogen for this Estrogen Receptor antibody (isoform 4) |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Estrogen Receptor antibody (isoform 4) and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
isoform 4), Estrogen Receptor (alpha |
| Short name: |
isoform 4), Estrogen Receptor Antibody (alpha |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
isoform 4), Estrogen Receptor (Antibody to) (a |
| Alternative technique: |
antibodies |