| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
XRCC4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the XRCC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This XRCC4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13426 |
| Purity: |
Antigen affinity |
| Description: |
Alternative transcription initiation and alternative splicing generates several transcript variants, The non-homologous end-joining pathway is required both for normal development and for suppression of tumors, This gene functionally complements XR-1 Chinese hamster ovary cell mutant, [provided by RefSeq], which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes, The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events |
| Immunogen: |
A portion of amino acids 205-234 from the human protein was used as the immunogen for this XRCC4 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the XRCC4 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
XRCC4 |
| Short name: |
XRCC4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
X-ray repair complementing defective repair in Chinese hamster cells 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
XRCC4 and IDBG-32219 and ENSG00000152422 and 7518, XRCC4 and IDBG-646520 and ENSBTAG00000024275 and 613590, Xrcc4 and IDBG-171005 and ENSMUSG00000021615 and 108138, nuclei, protein C-terminus binding, this GO :0001701 and in utero embryonic development and biological process this GO :0002328 and pro-B cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005958 and DNA-dependent protein kinase-DNA ligase 4 complex and cellular component this GO :0006266 and DNA ligation and biological process this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0007417 and central nervous system development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0010165 and response to X-ray and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0016032 and viral process and biological process this GO :0030054 and cell junction and cellular component this GO :0032807 and DNA ligase IV complex and cellular component this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033151 and V(D)J recombination and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051103 and DNA ligation involved in DNA repair and biological process this GO :0051351 and positive regulation of ligase activity and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071285 and cellular response to lithium ion and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, X-ray repair complementing defective repair in Chinese hamster cells 4 |
| Identity: |
12831 |
| Gene: |
XRCC4 |
More about : XRCC4 |
| Long gene name: |
X-ray repair cross complementing 4 |
| Synonyms gene name: |
X-ray repair complementing defective repair in Chinese hamster cells 4 |
| Synonyms name: |
X-ray repair, complementing defective, repair in Chinese hamster DNA repair protein XRCC4 |
| Locus: |
5q14, 2 |
| Discovery year: |
1990-10-16 |
| GenBank acession: |
AB017445 |
| Entrez gene record: |
7518 |
| Pubmed identfication: |
1697445 7665175 |
| RefSeq identity: |
NM_022550 |
| Havana BLAST/BLAT: |
OTTHUMG00000131319 |