| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DR6 (Death Receptor 6) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DR6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O75509 |
| Purity: |
Antigen affinity |
| Description: |
Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, This receptor has been shown to activate NF-kappaB and MAPK8/JNK, Through its death domain, and induce cell apoptosis, and may be involved in inflammation and immune regulation, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Immunogen: |
A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DR6 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DR6 (Death Receptor 6) |
| Short name: |
DR6 Antibody (Death Receptor 6) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DR6 (Antibody to) (Death Receptor 6) |
| Alternative technique: |
antibodies |
| Identity: |
13469 |
| Gene: |
TNFRSF21 |
More about : TNFRSF21 |
| Long gene name: |
TNF receptor superfamily member 21 |
| Synonyms gene name: |
member 21 , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR6 CD358 |
| Synonyms name: |
death receptor 6 |
| Locus: |
6p12, 3 |
| Discovery year: |
2001-07-27 |
| GenBank acession: |
AF068868 |
| Entrez gene record: |
27242 |
| Pubmed identfication: |
9714541 |
| RefSeq identity: |
NM_014452 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000014796 |