| Catalog number: | F45229-0.4ML |
|---|---|
| Price: | 2442 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | REST Antibody |
| Quantity: | 1000ug |
| Other quantities: | 0.08 ml 199€ 0.1mg 406€ 1 vial 521€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | REST |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | ELISA, WB |
| Recommended dilutions: | Western blot: 1:1000 |
| Notes: | Titration of the REST antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This REST antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | Q13127 |
| Purity: | Antigen affinity |
| Description: | Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, thereby acting as a chromatin modifier, which in turn recruit histone deacetylase to the promoters of REST-regulated genes, Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells |
| Immunogen: | A portion of amino acids 542-570 from the human protein was used as the immunogen for this REST antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the REST antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | REST |
| Short name: | REST Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | REST (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 9966 |
| Gene: | REST | More about : REST |
| Long gene name: | RE1 silencing transcription factor |
| Synonyms gene name: | RE1-silencing transcription factor |
| Synonyms: | NRSF XBR |
| Synonyms name: | neuron-restrictive silencer factor |
| Locus: | 4q12 |
| Discovery year: | 1996-04-12 |
| GenBank acession: | U13879 |
| Entrez gene record: | 5978 |
| Pubmed identfication: | 7871435 7697725 |
| RefSeq identity: | NM_005612 |
| Havana BLAST/BLAT: | OTTHUMG00000128770 |
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