REST Antibody

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Catalog number: F45229-0.4ML
Price: 2442 €
Supplier: MBS Recombinant Proteins
Product name: REST Antibody
Quantity: 1000ug
Other quantities: 0.08 ml 199€ 0.1mg 406€ 1 vial 521€
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More details :

Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: REST
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB
Recommended dilutions: Western blot: 1:1000
Notes: Titration of the REST antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This REST antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q13127
Purity: Antigen affinity
Description: Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, thereby acting as a chromatin modifier, which in turn recruit histone deacetylase to the promoters of REST-regulated genes, Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells
Immunogen: A portion of amino acids 542-570 from the human protein was used as the immunogen for this REST antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the REST antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: REST
Short name: REST Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: REST (Antibody to)
Alternative technique: antibodies
Identity: 9966
Gene: REST | More about : REST
Long gene name: RE1 silencing transcription factor
Synonyms gene name: RE1-silencing transcription factor
Synonyms: NRSF XBR
Synonyms name: neuron-restrictive silencer factor
Locus: 4q12
Discovery year: 1996-04-12
GenBank acession: U13879
Entrez gene record: 5978
Pubmed identfication: 7871435 7697725
RefSeq identity: NM_005612
Havana BLAST/BLAT: OTTHUMG00000128770

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