| Long name: |
NRSF/REST Primary Polyclonal Antibody |
| Also known as: |
NRSF/REST PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NRSF/REST |
| Specificity: |
This is a highly specific antibody against NRSF/REST |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
400-450/1097 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NRSF |
| Gene ID number: |
5978 |
| Swiss Prot: |
Q13127 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, Restricts the expression of neuronal genes by associating with two distinct corepressors, Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression, mSin3 and CoREST, thereby acting as a chromatin modifier, which in turn recruit histone deacetylase to the promoters of REST-regulated genes, Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NRSF, Neural-restrictive silencer factor, RE1-silencing transcription factor, REST, X2 box repressor, XBR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NRSF/REST |
| Short name: |
NRSF/REST Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NRSF/REST (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9966 |
| Gene: |
REST |
More about : REST |
| Long gene name: |
RE1 silencing transcription factor |
| Synonyms gene name: |
RE1-silencing transcription factor |
| Synonyms: |
NRSF XBR |
| Synonyms name: |
neuron-restrictive silencer factor |
| Locus: |
4q12 |
| Discovery year: |
1996-04-12 |
| GenBank acession: |
U13879 |
| Entrez gene record: |
5978 |
| Pubmed identfication: |
7871435 7697725 |
| RefSeq identity: |
NM_005612 |
| Havana BLAST/BLAT: |
OTTHUMG00000128770 |