| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Recoverin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the Recoverin antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Recoverin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35243 |
| Purity: |
Purified |
| Description: |
Binding of calcium to recoverin elicits a change in conformation that exposes the buried hydrophobic myristoyl moiety to interaction with cell membranes and other cellular proteins, Features common to this family include four calcium-binding EF-hand domains, Myristoylation, Recoverin is subject to the posttranslational modification of myristoylation, This family of proteins has been implicated in a broad range of cellular signaling functions, and Kv-channel interacting proteins (KchIPs), and an N-terminal myristoylation sequence, and ion channel regulation, gene expression, guanylate cyclase-activating proteins (GCAPs), has been shown to have functional significance for other calcium-binding protein family members, including phototransduction and neurotransmitter release, lipid metabolism, the post-translational addition of a fatty acid tail, visinin-like proteins (VILIPs), Recoverin belongs to a high-affinity calcium-binding family that includes neuronal calcium sensor-1 |
| Immunogen: |
A portion of amino acids 169-200 from the human protein was used as the immunogen for this Recoverin antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Recoverin antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Recoverin |
| Short name: |
Recoverin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Recoverin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9937 |
| Gene: |
RCVRN |
More about : RCVRN |
| Long gene name: |
recoverin |
| Synonyms gene: |
RCV1 |
| Locus: |
17p13, 1 |
| Discovery year: |
1992-11-09 |
| GenBank acession: |
BC001720 |
| Entrez gene record: |
5957 |
| Pubmed identfication: |
1387789 12507501 1467959 12789533 |
| RefSeq identity: |
NM_002903 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130268 |