| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PAX7 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the PAX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PAX7 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P23759 |
| Purity: |
Antigen affinity |
| Description: |
Members of this gene family typically contain a paired box domain, The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma, These genes play critical roles during fetal development and cancer growth, Three transcript variants encoding different isoforms have been found for this gene, an octapeptide, and a paired-type homeodomain, This gene is a member of the paired box (PAX) family of transcription factors |
| Immunogen: |
A portion of amino acids 181-210 from the human protein was used as the immunogen for this PAX7 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PAX7 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PAX7 |
| Short name: |
PAX7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
paired box 7 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010453 and regulation of cell fate commitment and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0014813 and satellite cell commitment and biological process this GO :0021527 and spinal cord association neuron differentiation and biological process this GO :0021904 and dorsal/ventral neural tube patterning and biological process this GO :0031062 and positive regulation of histone methylation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043393 and regulation of protein binding and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0051216 and cartilage development and biological process this GO :0060415 and muscle tissue morphogenesis and biological process this GO :2000288 and positive regulation of myoblast proliferation and biological process, HUP1 and PAX7B and RMS2, PAX7 and IDBG-645775 and ENSBTAG00000014967 and 536229, PAX7 and IDBG-92024 and ENSG00000009709 and 5081, Pax7 and IDBG-201015 and ENSMUSG00000028736 and 18509, nuclei, sequence-specific DNA binding, this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006355 and regulation of transcription, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, paired box 7 |
| Identity: |
8621 |
| Gene: |
PAX7 |
More about : PAX7 |
| Long gene name: |
paired box 7 |
| Synonyms gene name: |
paired box gene 7 |
| Synonyms: |
Hup1 |
| Locus: |
1p36, 13 |
| Discovery year: |
1992-11-20 |
| GenBank acession: |
X96743 |
| Entrez gene record: |
5081 |
| Pubmed identfication: |
7981748 8431641 |
| RefSeq identity: |
NM_002584 |
| Classification: |
PRD class homeoboxes and pseudogenes Paired boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000002433 |