| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cyclin D2 (CCND2) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Cyclin D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Cyclin D2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P30279 |
| Purity: |
Antigen affinity |
| Description: |
Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, High level expression of this gene was observed in ovarian and testicular tumors, Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation, This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb, whose activity is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin D2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Cyclin D2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cyclin D2 (CCND2) |
| Short name: |
Cyclin D2 Antibody (CCND2) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclin D2 (Antibody to) (CCND2) |
| Alternative technique: |
antibodies |
| Identity: |
1583 |
| Gene: |
CCND2 |
More about : CCND2 |
| Long gene name: |
cyclin D2 |
| Synonyms name: |
G1/S-specific cyclin D2 |
| Locus: |
12p13, 32 |
| Discovery year: |
1991-12-10 |
| GenBank acession: |
AF518005 |
| Entrez gene record: |
894 |
| Pubmed identfication: |
1386335 |
| RefSeq identity: |
NM_001759 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000168123 |