| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPV3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the TRPV3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRPV3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8K424 |
| Purity: |
Purified |
| Description: |
Activation exhibits an outward rectification, Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) (By similarity), It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius, May associate with TRPV1 and may modulate its activity, [UniProt], TRPV3 is a putative receptor-activated non-selective calcium permeant cation channel |
| Immunogen: |
A portion of amino acids 90-119 from the mouse protein was used as the immunogen for this TRPV3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPV3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPV3 |
| Short name: |
TRPV3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPV3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Synonyms: |
VRL3 |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |