| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
WNT3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This WNT3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P56703 |
| Purity: |
Antigen affinity |
| Description: |
It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse, These proteins have been implicated in oncogenesis and in several developmental processes, This gene is a member of the WNT gene family, This gene is clustered with WNT15, and 84% to human WNT3A protein, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway, another WNT gene product, another family member, in the chromosome 17q21 region, including regulation of cell fate and patterning during embryogenesis, lung, rectal, The WNT gene family consists of structurally related genes which encode secreted signaling proteins |
| Immunogen: |
A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the WNT3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
WNT3 |
| Short name: |
WNT3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 3 (Antibody to), wingless-classification MMTV integration site family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Extracellular, INT4, WNT3 and IDBG-55691 and ENSG00000108379 and 101929777, Wnt3 and IDBG-213058 and ENSMUSG00000000125 and 22415, member 3, receptor a this GO nist activity, this GO :0000902 and cell morphogenesis and biological process this GO :0001707 and mesoderm formation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007276 and gamete generation and biological process this GO :0007411 and axon guidance and biological process this GO :0009948 and anterior/posterior axis specification and biological process this GO :0009950 and dorsal/ventral axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0035115 and embryonic forelimb morphogenesis and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0044338 and canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation and biological process this GO :0044339 and canonical Wnt receptor signaling pathway involved in osteoblast differentiation and biological process this GO :0045165 and cell fate commitment and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048646 and anatomical structure formation involved in morphogenesis and biological process this GO :0048697 and positive regulation of collateral sprouting in absence of injury and biological process this GO :0048843 and negative regulation of axon extension involved in axon guidance and biological process this GO :0060064 and Spemann organizer formation at the anterior end of the primitive streak and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060173 and limb development and biological process this GO :0060174 and limb bud formation and biological process this GO :0060323 and head morphogenesis and biological process this GO :0061180 and mammary gland epithelium development and biological process this GO :0071300 and cellular response to retinoic acid and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005109 : frizzled binding and also this GO :0005515 : protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0048018 : receptor a this GO nist activity, this GO :0005109 : frizzled binding, this GO :0005515 : protein binding, this GO :0019904 : protein domain specific binding, this GO :0048018 : receptor a this GO nist activity, 7473, 88369 and IDBG-641199 and ENSBTAG00000016012 and 540753, wingless-type MMTV integration site family |
| Identity: |
12782 |
| Gene: |
WNT3 |
More about : WNT3 |
| Long gene name: |
Wnt family member 3 |
| Synonyms gene: |
INT4 |
| Synonyms gene name: |
member 3 , wingless-type MMTV integration site family |
| Synonyms: |
MGC131950 MGC138321 MGC138323 |
| Synonyms name: |
WNT-3 proto-oncogene protein |
| Locus: |
17q21, 31-q21, 32 |
| Discovery year: |
1989-05-30 |
| GenBank acession: |
AY009397 |
| Entrez gene record: |
7473 |
| Pubmed identfication: |
8244403 |
| RefSeq identity: |
NM_030753 |
| Classification: |
Wnt family Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000178076 |