| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
BAFF Receptor |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the BAFF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This BAFF Receptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q96RJ3 |
| Purity: |
Antigen affinity |
| Description: |
Also, It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival, Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE), The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain, Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells, some SLE patients have increased levels of BAFF in serum, B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this BAFF Receptor antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the BAFF Receptor antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
BAFF Receptor |
| Short name: |
BAFF Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BAFF Receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11929 |
| Gene: |
TNFSF13B |
More about : TNFSF13B |
| Long gene name: |
tumor necrosis factor superfamily member 13b |
| Synonyms gene: |
TNFSF20 |
| Synonyms gene name: |
member 13b , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
BAFF THANK BLYS TALL-1 TALL1 CD257 |
| Locus: |
13q33, 3 |
| Discovery year: |
1999-07-19 |
| GenBank acession: |
AF136293 |
| Entrez gene record: |
10673 |
| Pubmed identfication: |
10331498 10359578 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000017329 |