| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PITX2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This PITX2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q99697 |
| Purity: |
Antigen affinity |
| Description: |
A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development, Alternatively spliced transcript variants encoding distinct isoforms have been described, Mutations in this gene are associated with Axenfeld-Rieger syndrome, The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression, This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin, and sporadic cases of Peters anomaly, iridogoniodysgenesis syndrome, is involved in the development of the eye, tooth and abdominal organs, which is in the bicoid class of homeodomain proteins, This gene encodes a member of the RIEG/PITX homeobox family |
| Immunogen: |
A portion of amino acids 42-71 from the human protein was used as the immunogen for this PITX2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PITX2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PITX2 |
| Short name: |
PITX2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PITX2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9005 |
| Gene: |
PITX2 |
More about : PITX2 |
| Long gene name: |
paired like homeodomain 2 |
| Synonyms gene: |
IRID2 IHG2 RIEG RIEG1 RGS |
| Synonyms gene name: |
paired-like homeodomain transcription factor 2 paired-like homeodomain 2 |
| Synonyms: |
IGDS RS Brx1 Otlx2 ARP1 |
| Locus: |
4q25 |
| Discovery year: |
1992-10-05 |
| GenBank acession: |
U69961 |
| Entrez gene record: |
5308 |
| Pubmed identfication: |
9539779 7581385 |
| Classification: |
PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000132837 |