| Alternative name 1: |
Clone: 1F6, Mab anti-, IRAK3 |
| Alternative name 2: |
Clone: 1F6, Mab antibody-, IRAK3 |
| Alternative name 3: |
Clone: 1F6, Mab antibody-, IRAK3 |
| Alternative name 4: |
anti-IRAK3 Clone: 1F6 |
| Alternative name 5: |
IRAK3 Clone: 1F6 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1F6, IRAK3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 1F6, IRAK3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1F6, interleukin-1 receptor-associated kinase 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
ASRT5 and IRAKM, IRAK3 and IDBG-45584 and ENSG00000090376 and 11213, IRAKM and IDBG-634310 and ENSBTAG00000007636 and 510342, Irak3 and IDBG-192499 and ENSMUSG00000020227 and 73914, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0001960 and negative regulation of cytokine-mediated signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0009615 and response to virus and biological process this GO :0010933 and positive regulation of macrophage tolerance induction and biological process this GO :0010936 and negative regulation of macrophage cytokine production and biological process this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043242 and negative regulation of protein complex disassembly and biological process this GO :0043244 and regulation of protein complex disassembly and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070498 and interleukin-1-mediated signaling pathway and biological process this GO :0070555 and response to interleukin-1 and biological process, interleukin-1 receptor-associated kinase 3 |
| Identity: |
17020 |
| Gene: |
IRAK3 |
More about : IRAK3 |
| Long gene name: |
interleukin 1 receptor associated kinase 3 |
| Synonyms gene name: |
interleukin-1 receptor-associated kinase 3 |
| Synonyms: |
IRAK-M |
| Locus: |
12q14, 3 |
| Discovery year: |
2002-07-17 |
| GenBank acession: |
AF113136 |
| Entrez gene record: |
11213 |
| Pubmed identfication: |
10383454 |
| Havana BLAST/BLAT: |
OTTHUMG00000169002 |