| Also known as: |
MSX2 / MSH |
| Other names: |
Homeobox protein Hox-8, Homeobox protein MSX-2, homeobox protein Hox-8, homeobox protein MSX-2, msh homeo box 2, msh homeobox 2, msh homeobox homolog 2, homeobox protein MSX-2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MSX2 |
| Gene name synonims: |
MSH |
| Other gene names: |
CRS2, FPP, HOX8, HOX8, MSH, MSX2, PFM, PFM1, MSX2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
1F6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 1F6] (IgG2a, k) MSX2 / MSH |
| Short name: |
Mouse Monoclonal [clone 1F6] (IgG2a, k) MSX2 / MSH Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens msh homeobox 2 / MSH (Antibody to), Mouse monoclonal [clonality 1F6] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CRS2 and FPP and HOX8 and MSH and PFM and PFM1, DNA-templated and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0051216 and cartilage development and biological process this GO :0051795 and positive regulation of catagen and biological process this GO :0060346 and bone trabecula formation and biological process this GO :0060349 and bone morphogenesis and biological process this GO :0060363 and cranial suture morphogenesis and biological process this GO :0060364 and frontal suture morphogenesis and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0061180 and mammary gland epithelium development and biological process this GO :0061312 and BMP signaling pathway involved in heart development and biological process this GO :0070166 and enamel mineralization and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0090427 and activation of meiosis and biological process this GO :2000678 and negative regulation of transcription regulatory region DNA binding and biological process this GO :2001055 and positive regulation of mesenchymal cell apoptotic process and biological process, MSX2 and IDBG-58312 and ENSG00000120149 and 4488, MSX2 and IDBG-628518 and ENSBTAG00000013873 and 540230, Msx2 and IDBG-153222 and ENSMUSG00000021469 and 17702, nuclei, spreading of epidermal cells and biological process this GO :0035880 and embryonic nail plate morphogenesis and biological process this GO :0042060 and wound healing and biological process this GO :0042476 and odontogenesis and biological process this GO :0042640 and anagen and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045617 and negative regulation of keratinocyte differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000982 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity and molecular function this GO :0000989 and transcription factor binding transcription factor activity and molecular function this GO :0001227 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001503 and ossification and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0002063 and chondrocyte development and biological process this GO :0002076 and osteoblast development and biological process this GO :0003148 and outflow tract septum morphogenesis and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003198 and epithelial to mesenchymal transition involved in endocardial cushion formation and biological process this GO :0003416 and endochondral bone growth and biological process this GO :0003677 and DNA binding and molecular function this GO :0003712 and transcription cofactor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0023019 and signal transduction involved in regulation of gene expression and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0032792 and negative regulation of CREB transcription factor activity and biological process this GO :0035115 and embryonic forelimb morphogenesis and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0035313 and wound healing, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000982 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity and also this GO :0000989 : transcription factor binding transcription factor activity and also this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003712 : transcription cofactor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000982 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, this GO :0000989 : transcription factor binding transcription factor activity, this GO :0001227 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003712 : transcription cofactor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, transcription regulatory region DNA binding, msh homeobox 2 |
| Identity: |
7392 |
| Gene: |
MSX2 |
More about : MSX2 |
| Long gene name: |
msh homeobox 2 |
| Synonyms gene: |
PFM1 |
| Synonyms gene name: |
msh (Drosophila) homeo box homolog 2 parietal foramina 1 msh homeobox homolog 2 (Drosophila) |
| Synonyms: |
CRS2 FPP HOX8 MSH PFM |
| Synonyms name: |
craniosynostosis, type 2 |
| Locus: |
5q35, 2 |
| Discovery year: |
1993-05-26 |
| GenBank acession: |
D26145 |
| Entrez gene record: |
4488 |
| Pubmed identfication: |
8668339 8786091 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000130556 |