| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ABCD2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Intented use: |
This ABCD2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UBJ2 |
| Purity: |
Antigen affinity |
| Description: |
ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intra-cellular membranes, ALD, All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter, GCN20, MDR/TAP, MRP, Mutations in this gene have been observed in patients with adrenoleukodystrophy, OABP, The function of this peroxisomal membrane protein is unknown, This gene has been identified as a candidate for a modifier gene, This gene is also a candidate for a complement group of Zellweger syndrome, This protein is a member of the ALD subfamily, White), a genetically heterogeneous disorder of peroxisomal biogenesis, a severe demyelinating disease, accounting for the extreme variation among adrenoleukodystrophy phenotypes, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle, The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters |
| Immunogen: |
A portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ABCD2 antibody and store frozen at -20 deg |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ABCD2 |
| Short name: |
ABCD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 2 (Antibody to), sub-family D (ALD), adenosine triphosphate-binding cassette |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABC39 and ALDL1 and ALDR and ALDRP and hALDR, ABCD2 and IDBG-26995 and ENSG00000173208 and 225, ATPase activity, Abcd2 and IDBG-175455 and ENSMUSG00000055782 and 26874, BT, Plasma membranes, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and also this GO :0042803 : protein homodimerization activity, coupled to transmembrane movement of substances and molecular function this GO :0042760 and very long-chain fatty acid catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0055085 and transmembrane transport and biological process, member 2, sub-family D (ALD), this GO :0000038 and very long-chain fatty acid metabolic process and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006635 and fatty acid beta-oxidation and biological process this GO :0006810 and transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0042626 and ATPase activity, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016887 : ATPase activity and also this GO :0042626 : ATPase activity, this GO :0005524 : ATP binding, this GO :0016887 : ATPase activity, this GO :0042626 : ATPase activity, this GO :0042803 : protein homodimerization activity, 526436, 101909154, 87418 and IDBG-633512 and ENSBTAG00000038043 and 100335783, ATP-binding cassette |
| Identity: |
66 |
| Gene: |
ABCD2 |
More about : ABCD2 |
| Long gene name: |
ATP binding cassette subfamily D member 2 |
| Synonyms gene: |
ALDL1 |
| Synonyms gene name: |
ATP-binding cassette, member 2 , sub-family D (ALD) |
| Synonyms: |
ALDR ALDRP |
| Locus: |
12q12 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
U28150 |
| Entrez gene record: |
225 |
| Pubmed identfication: |
8577752 |
| RefSeq identity: |
NM_005164 |
| Classification: |
ATP binding cassette subfamily D |
| Havana BLAST/BLAT: |
OTTHUMG00000169337 |