| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
XCR1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the XCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This XCR1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P46094 |
| Purity: |
Antigen affinity |
| Description: |
It transduces a signal by increasing the intracellular calcium ions level, The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids, The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling, This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor, Two alternatively spliced transcript variants encoding the same protein have been found for this gene, The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily |
| Immunogen: |
A portion of amino acids 305-333 from the human protein was used as the immunogen for this XCR1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the XCR1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
XCR1 |
| Short name: |
XCR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C motif) receptor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CCXCR1 and GPR5, Plasma membranes, XCR1 and IDBG-30030 and ENSG00000173578 and 2829, Xcr1 and IDBG-206508 and ENSMUSG00000060509 and 23832, chemokine receptor activity, coupled to cyclic nucleotide second messenger and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0034097 and response to cytokine and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007187 and G-protein coupled receptor signaling pathway, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity, this GO :0004950 : chemokine receptor activity, 106550 and IDBG-647812 and ENSBTAG00000020019 and 617880, chemokine (C motif) receptor 1 |
| Identity: |
1625 |
| Gene: |
XCR1 |
More about : XCR1 |
| Long gene name: |
X-C motif chemokine receptor 1 |
| Synonyms gene: |
GPR5 CCXCR1 |
| Synonyms gene name: |
chemokine (C motif) XC receptor 1 chemokine (C motif) receptor 1 |
| Locus: |
3p21, 31 |
| Discovery year: |
1994-07-25 |
| Entrez gene record: |
2829 |
| Pubmed identfication: |
7832990 10400311 |
| Classification: |
X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133449 |