| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ID1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the ID1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ID1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P41134 |
| Purity: |
Antigen affinity |
| Description: |
The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts, This protein may play a role in cell growth, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], and differentiation, senescence, The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors |
| Immunogen: |
A portion of amino acids 66-93 from the human protein was used as the immunogen for this ID1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ID1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ID1 |
| Short name: |
ID1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
dominant negative helix-loop-helix protein (Antibody to), inhibitor on Desoxyribonucleic acid binding 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0010621 and negative regulation of transcription by transcription factor localization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0031648 and protein destabilization and biological process this GO :0032963 and collagen metabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043534 and blood vessel endothelial cell migration and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048514 and blood vessel morphogenesis and biological process this GO :0060425 and lung morphogenesis and biological process this GO :0060426 and lung vasculature development and biological process, ID1 and IDBG-63543 and ENSG00000125968 and 3397, ID1 and IDBG-641533 and ENSBTAG00000016169 and 497011, Id1 and IDBG-209844 and ENSMUSG00000042745 and 15901, bHLHb24 and ID, dominant negative helix-loop-helix protein, nuclei, protein dimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001525 and angiogenesis and biological process this GO :0001886 and endothelial cell morphogenesis and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006351 and transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0046983 : protein dimerization activity, this GO :0005515 : protein binding, this GO :0046983 : protein dimerization activity, inhibitor of DNA binding 1 |
| Identity: |
5360 |
| Gene: |
ID1 |
More about : ID1 |
| Long gene name: |
HLH protein , inhibitor of DNA binding 1 |
| Synonyms gene name: |
dominant negative helix-loop-helix protein , inhibitor of DNA binding 1 |
| Synonyms: |
dJ857M17, 1, 2 bHLHb24 |
| Synonyms name: |
DNA-binding protein inhibitor ID-1 inhibitor of differentiation 1 |
| Locus: |
20q11, 21 |
| Discovery year: |
1994-12-22 |
| Entrez gene record: |
3397 |
| Pubmed identfication: |
8294468 |
| RefSeq identity: |
NM_002165 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000032181 |