| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ISG15 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ISG15 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ISG15 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05161 |
| Purity: |
Antigen affinity |
| Description: |
B-lymphocyte, Enhancement of NK cell proliferation, ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, ISG15 has has also been shown to function intracellularly as a ubiquitin homolog, ISG15 is secreted also by cell lines of monocyte, Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , T-lymphocyte, The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression, and by influenza B virus, and epithelial origins, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta, augmentation of non-major histocompatibility complex-restricted cytotoxicity, but not IFN-gamma , human fibroblasts, ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity |
| Immunogen: |
A portion of amino acids 31-61 from the human protein was used as the immunogen for this ISG15 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ISG15 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ISG15 |
| Short name: |
ISG15 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ISG15 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4053 |
| Gene: |
ISG15 |
More about : ISG15 |
| Long gene name: |
ISG15 ubiquitin-like modifier |
| Synonyms gene: |
G1P2 |
| Synonyms gene name: |
alpha-inducible protein (clone IFI-15K) , interferon |
| Synonyms: |
IFI15 UCRP |
| Locus: |
1p36, 33 |
| Discovery year: |
1990-10-16 |
| GenBank acession: |
BC009507 |
| Entrez gene record: |
9636 |
| Pubmed identfication: |
3087979 |
| RefSeq identity: |
NM_005101 |
| Havana BLAST/BLAT: |
OTTHUMG00000040777 |