| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NUMB |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the NUMB antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This NUMB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P49757 |
| Purity: |
Purified |
| Description: |
Four transcript variants encoding different isoforms have been found for this gene, LNX1, The encoded protein, and NOTCH1, is a membrane-bound protein that has been shown to associate with EPS15, whose degradation is induced in a proteasome-dependent manner by MDM2, The protein encoded by this gene plays a role in the determination of cell fates during development |
| Immunogen: |
A portion of amino acids 1-30 from the human protein was used as the immunogen for this NUMB antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the NUMB antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NUMB |
| Short name: |
NUMB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NUMB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8060 |
| Gene: |
NUMB |
More about : NUMB |
| Long gene name: |
NUMB, endocytic adaptor protein |
| Synonyms gene: |
C14orf41 |
| Synonyms gene name: |
numb (Drosophila) homolog chromosome 14 open reading frame 41 numb homolog (Drosophila) |
| Locus: |
14q24, 3 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
L40393 |
| Entrez gene record: |
8650 |
| Pubmed identfication: |
11121447 |
| Havana BLAST/BLAT: |
OTTHUMG00000171436 |