| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CYP1A2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CYP1A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CYP1A2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P05177 |
| Purity: |
Antigen affinity |
| Description: |
Also acts in the metabolism of aflatoxin B1 and acetaminophen, CYP1A2 is involved in an NADPH-dependent electron transport pathway, Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation, Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Most active in catalyzing 2-hydroxylation, Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines, [UniProt], and xenobiotics, fatty acids, including steroids, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Immunogen: |
A portion of amino acids 255-282 from the human protein was used as the immunogen for this CYP1A2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CYP1A2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CYP1A2 |
| Short name: |
CYP1A2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CYP1A2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2596 |
| Gene: |
CYP1A2 |
More about : CYP1A2 |
| Long gene name: |
cytochrome P450 family 1 subfamily A member 2 |
| Synonyms gene name: |
cytochrome P450, family 1, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily I (aromatic compound-inducible) |
| Synonyms: |
P3-450 CP12 |
| Locus: |
15q24, 1 |
| Discovery year: |
1990-04-25 |
| GenBank acession: |
AF182274 |
| Entrez gene record: |
1544 |
| Pubmed identfication: |
15128046 |
| RefSeq identity: |
NM_000761 |
| Classification: |
Cytochrome P450 family 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000172901 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP) Allele Nomenclature Committee |