| Long name: |
2, 2) Monoclonal Antibody, CYP1A2 (499CT13 |
| Also known as: |
2, 2) Monoclonal Antibody, CYP1A2 (499CT13 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CYP1A2 |
| Specificity: |
This is a highly specific antibody against CYP1A2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
2, 2, 499CT13 |
| Source: |
This CYP1A2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from human CYP1A2 |
| Gene ID number: |
1544 |
| Swiss Prot: |
P05177 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100~250) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also acts in the metabolism of aflatoxin B1 and acetaminophen, Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation, Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Most active in catalyzing 2-hydroxylation, Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines, and xenobiotics, fatty acids, including steroids, this enzyme is involved in an NADPH-dependent electron transport pathway, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Purification method: |
This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CYP1A2, CYPIA2, Cholesterol 25-hydroxylase, Cytochrome P(3)450, Cytochrome P450 1A2, Cytochrome P450 4, Cytochrome P450-P3, P3-450, P450(PA), CP12 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
2, 2) Monoclonal, CYP1A2 (499CT13 |
| Short name: |
2, 2) Monoclonal Antibody, CYP1A2 (499CT13 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
2, 2) monoclonal (Antibody to), CYP1A2 (499CT13 |
| Alternative technique: |
antibodies |
| Identity: |
2596 |
| Gene: |
CYP1A2 |
More about : CYP1A2 |
| Long gene name: |
cytochrome P450 family 1 subfamily A member 2 |
| Synonyms gene name: |
cytochrome P450, family 1, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily I (aromatic compound-inducible) |
| Synonyms: |
P3-450 CP12 |
| Locus: |
15q24, 1 |
| Discovery year: |
1990-04-25 |
| GenBank acession: |
AF182274 |
| Entrez gene record: |
1544 |
| Pubmed identfication: |
15128046 |
| RefSeq identity: |
NM_000761 |
| Classification: |
Cytochrome P450 family 1 |
| Havana BLAST/BLAT: |
OTTHUMG00000172901 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP) Allele Nomenclature Committee |