| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DLK |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the DLK antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This DLK antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P80370 |
| Purity: |
Antigen affinity |
| Description: |
A polymorphism within this gene has been associated with child and adolescent obesity, Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14), It is one of several imprinted genes located in a region of on chr 14q32, The mode of inheritance for this polymorphism is polar overdominance, The protein is involved in the differentiation of several cell types, This gene is expressed from the paternal allele, including adipocytes, it is also thought to be a tumor suppressor, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass, This gene encodes a transmembrane protein containing six epidermal growth factor repeats |
| Immunogen: |
This DLK antibody was produced from rabbits immunized with a recombinant protein of human DLK |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DLK antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DLK |
| Short name: |
DLK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DLK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6851 |
| Gene: |
MAP3K12 |
More about : MAP3K12 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase 12 |
| Synonyms gene: |
ZPK |
| Synonyms: |
MUK DLK ZPKP1 MEKK12 |
| Synonyms name: |
dual leucine zipper kinase DLK |
| Locus: |
12q13, 13 |
| Discovery year: |
1994-09-29 |
| GenBank acession: |
U07358 |
| Entrez gene record: |
7786 |
| Pubmed identfication: |
8037767 |
| RefSeq identity: |
NM_006301 |
| Classification: |
Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000169854 |