TNFR1 Antibody

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Catalog number: F41241-0.08ML
Price: 199 €
Supplier: NJS poly
Product name: TNFR1 Antibody
Quantity: 0.08 ml
Other quantities: 0.1mg 389€ 0.4 ml 406€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: TNFR1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, FACS, WB
Recommended dilutions: Flow Cytometry: 1:10-1:50, Western blot: 1:1000
Notes: Titration of the TNFR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This TNFR1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: P19438
Purity: Antigen affinity
Description: Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome, The impaired receptor clearance is thought to be a mechanism of the disease, This protein is one of the major receptors for the tumor necrosis factor-alpha, This receptor can activate NF-kappaB, and function as a regulator of inflammation, and thus play regulatory roles in the signal transduction mediated by the receptor, mediate apoptosis, The protein encoded by this gene is a member of the TNF-receptor superfamily
Immunogen: A portion of amino acids 252-281 from the human protein was used as the immunogen for this TNFR1 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TNFR1 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: TNFR1
Short name: TNFR1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: TNFR1 (Antibody to)
Alternative technique: antibodies
Identity: 11916
Gene: TNFRSF1A | More about : TNFRSF1A
Long gene name: TNF receptor superfamily member 1A
Synonyms gene: TNFR1
Synonyms gene name: member 1A , tumor necrosis factor receptor superfamily
Synonyms: TNF-R TNFAR TNFR60 TNF-R-I CD120a TNF-R55
Locus: 12p13, 31
Discovery year: 1991-01-15
GenBank acession: M75866
Entrez gene record: 7132
Pubmed identfication: 1655358 2158863
RefSeq identity: NM_001065
Classification: CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT: OTTHUMG00000168267
Locus Specific Databases: INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations LRG_193

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