| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CAD |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the CAD antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CAD antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P27708 |
| Purity: |
Antigen affinity |
| Description: |
This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, and dihydroorotase, aspartate transcarbamoylase, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides, The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate |
| Immunogen: |
A portion of amino acids 780-809 from the human protein was used as the immunogen for this CAD antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CAD antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CAD |
| Short name: |
CAD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CAD (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1424 |
| Gene: |
CAD |
More about : CAD |
| Long gene name: |
and dihydroorotase , aspartate transcarbamylase, carbamoyl-phosphate synthetase 2 |
| Locus: |
2p23, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
D78586 |
| Entrez gene record: |
790 |
| Pubmed identfication: |
8619816 2565865 |
| Havana BLAST/BLAT: |
OTTHUMG00000097070 |