| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CDKN2C |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the CDKN2C antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This CDKN2C antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42773 |
| Purity: |
Antigen affinity |
| Description: |
Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function, Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, This protein has been shown to interact with CDK4 or CDK6, Two alternatively spliced transcript variants of this gene, and prevent the activation of the CDK kinases, as well as in suppressing tumorigenesis, have been reported, thus function as a cell growth regulator that controls cell cycle G1 progression, which encode an identical protein, The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors |
| Immunogen: |
A portion of amino acids 113-139 from the human protein was used as the immunogen for this CDKN2C antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CDKN2C antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CDKN2C |
| Short name: |
CDKN2C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
inhibits cyclin-dependent kinase 4) (Antibody to), cyclin-dependent kinase inhibitor 2C (p18 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDKN2C and IDBG-639655 and ENSBTAG00000011059 and 505691, CDKN2C and IDBG-98423 and ENSG00000123080 and 1031, Cdkn2c and IDBG-174648 and ENSMUSG00000028551 and 12580, INK4C and p18 and p18-INK4C, inhibits CDK4), nuclei, protein kinase binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007050 and cell cycle arrest and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0048709 and oli this GO dendrocyte differentiation and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861 : cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, cyclin-dependent kinase inhibitor 2C (p18 |
| Identity: |
1789 |
| Gene: |
CDKN2C |
More about : CDKN2C |
| Long gene name: |
cyclin dependent kinase inhibitor 2C |
| Synonyms gene name: |
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| Synonyms: |
INK4C p18 |
| Locus: |
1p32, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
BC000598 |
| Entrez gene record: |
1031 |
| Pubmed identfication: |
8001816 9636670 |
| RefSeq identity: |
NM_001262 |
| Classification: |
Ankyrin repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000008046 |