Dnmt3b Antibody

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Catalog number: F40611-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: Dnmt3b Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 1 vial 521€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: Dnmt3b
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, IHC, WB
Recommended dilutions: IHC (Paraffin): 1:10-1:50, Western blot: 1:2000
Notes: Titration of the Dnmt3b antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This Dnmt3b antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q9UBC3
Purity: Purified
Description: Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome, Studies in mice have demonstrated that DNA methylation is required for mammalian development, The protein localizes primarily to the nucleus and its expression is developmentally regulated, and X-chromosome inactivation, imprinting, rather than maintenance methylation, CpG methylation is an epigenetic modification that is important for embryonic development
Immunogen: A portion of amino acids 389-417 from the human protein was used as the immunogen for this Dnmt3b antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Dnmt3b antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: Dnmt3b
Short name: Dnmt3b Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: Dnmt3b (Antibody to)
Alternative technique: antibodies
Identity: 2979
Gene: DNMT3B | More about : DNMT3B
Long gene name: DNA methyltransferase 3 beta
Synonyms gene name: DNA (cytosine-5-)-methyltransferase 3 beta
Locus: 20q11, 21
Discovery year: 1998-07-15
Entrez gene record: 1789
Pubmed identfication: 9662389 10433969
RefSeq identity: NM_006892
Classification: PWWP domain containing
Havana BLAST/BLAT: OTTHUMG00000032226
Locus Specific Databases: DNMT3Bbase: Mutation registry for ICF syndrome LRG_56

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