| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FUS |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, IF, IHC, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the FUS antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This FUS antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35637 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing results in multiple transcript variants, Defects in this gene result in amyotrophic lateral sclerosis type 6, The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm, This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing, This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex |
| Immunogen: |
A portion of amino acids 499-526 from the human protein was used as the immunogen for this FUS antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FUS antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FUS |
| Short name: |
FUS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FUS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4010 |
| Gene: |
FUS |
More about : FUS |
| Long gene name: |
FUS RNA binding protein |
| Synonyms gene: |
ALS6 |
| Synonyms gene name: |
derived from t(12, fusion, 16) in malignant liposarcoma) fused in sarcoma , 16) malignant liposarcoma amyotrophic lateral sclerosis 6 fusion (involved in t(12 |
| Synonyms: |
TLS FUS1 hnRNP-P2 HNRNPP2 |
| Synonyms name: |
heterogeneous nuclear ribonucleoprotein P2 translocated in liposarcoma |
| Locus: |
16p11, 2 |
| Discovery year: |
1992-11-26 |
| GenBank acession: |
AF071213 |
| Entrez gene record: |
2521 |
| Pubmed identfication: |
2372777 7503811 19251628 19251627 |
| RefSeq identity: |
NM_004960 |
| Classification: |
Zinc fingers RANBP2-type RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132395 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_655 |