| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
STIM1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the STIM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This STIM1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13586 |
| Purity: |
Antigen affinity |
| Description: |
Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, It is one of several genes located in the imprinted gene domain of 11p15, This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), This gene may play a role in malignancies and disease that involve this region, Wilms tumor, adrenocrotical carcinoma, an important tumor-suppressor gene region, and breast cancer, and lung, as well as early hematopoiesis, by mediating attachment to stromal cells, ovarian, rhabdomyosarcoma, with the 3' end of this gene situated 1, 5, 6 kb from the 5' end of the RRM1 gene, This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs) |
| Immunogen: |
A portion of amino acids 509-538 from the human protein was used as the immunogen for this STIM1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the STIM1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
STIM1 |
| Short name: |
STIM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
STIM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11386 |
| Gene: |
STIM1 |
More about : STIM1 |
| Long gene name: |
stromal interaction molecule 1 |
| Synonyms: |
GOK D11S4896E |
| Locus: |
11p15, 4 |
| Discovery year: |
1997-02-05 |
| GenBank acession: |
BC021300 U52426 |
| Entrez gene record: |
6786 |
| Pubmed identfication: |
8921403 11463338 11983428 |
| RefSeq identity: |
NM_003156 |
| Classification: |
Sterile alpha motif domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133360 |
| Locus Specific Databases: |
LRG_164 |