TLK2 Antibody

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Catalog number: F40173-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: TLK2 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1ml 263€ 1 vial 521€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: TLK2
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB
Recommended dilutions: Western blot: 1:1000
Notes: Titration of the TLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This TLK2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q86UE8
Purity: Purified
Description: It is inactivated by phosphorylation at Ser-750, TLK2 heterodimerizes with TLK1, The TLK2 enzyme is cell-cycle regulated, This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly, This nuclear protein is widely expressed, a member of the Ser/Thr protein kinase family, and in several adult cell lines, heart and skeletal muscle tissues, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase, kidney, liver, pancreas, potentially by CHK1, with maximal activity in S-phase, with presence in fetal placenta, TLK2
Immunogen: A portion of amino acids 141-171 from the human protein was used as the immunogen for this TLK2 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TLK2 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: TLK2
Short name: TLK2 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: TLK2 (Antibody to)
Alternative technique: antibodies
Identity: 11842
Gene: TLK2 | More about : TLK2
Long gene name: tousled like kinase 2
Synonyms gene name: tousled-like kinase 2
Synonyms: PKU-ALPHA MGC44450
Locus: 17q23
Discovery year: 2000-01-07
GenBank acession: AB004884
Entrez gene record: 11011
Pubmed identfication: 9427565 10523312
RefSeq identity: NM_006852
Havana BLAST/BLAT: OTTHUMG00000179176

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