| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPM7 (CHAK1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the TRPM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRPM7 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q96QT4 |
| Purity: |
Purified |
| Description: |
As a channel, As a kinase, TRP-PLIK is a protein that is both an ion channel and a kinase, The kinase activity is necessary for channel function, are ion channels that are thought to mediate capacitative calcium entry into the cell, as shown by its dependence on intracellular ATP and by the kinase mutants, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium, it is capable of phosphorylating itself and other substrates, mammalian homologs of the Drosophila transient receptor potential (trp) protein, TRPCs, [supplied by OMIM] |
| Immunogen: |
A portion of amino acids 45-74 from the human protein was used as the immunogen for this TRPM7 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPM7 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPM7 (CHAK1) |
| Short name: |
TRPM7 Antibody (CHAK1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 7 (Antibody to) (CHAK1), subfamily M, transient receptor potential cation channel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, TRPM7 and IDBG-11807 and ENSG00000092439 and 54822, TRPM7 and IDBG-646663 and ENSBTAG00000031165 and 514642, Trpm7 and IDBG-204376 and ENSMUSG00000027365 and 58800, member 7, subfamily M, this GO :0001726 and ruffle and cellular component this GO :0003779 and actin binding and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016301 and kinase activity and molecular function this GO :0016340 and calcium-dependent cell-matrix adhesion and biological process this GO :0016772 and transferase activity, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0005216 : ion channel activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0005216 : ion channel activity, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0017022 : myosin binding, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017022 : myosin binding and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0017022 and myosin binding and molecular function this GO :0031032 and actomyosin structure organization and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0055085 and transmembrane transport and biological process this GO :0070266 and necroptotic process and biological process this GO :0070588 and calcium ion transmembrane transport and biological process, transient receptor potential cation channel |
| Identity: |
17994 |
| Gene: |
TRPM7 |
More about : TRPM7 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 7 |
| Synonyms gene name: |
member 7 , subfamily M, transient receptor potential cation channel |
| Synonyms: |
CHAK1 LTRPC7 TRP-PLIK |
| Locus: |
15q21, 2 |
| Discovery year: |
2002-01-11 |
| GenBank acession: |
AF346629 |
| Entrez gene record: |
54822 |
| Pubmed identfication: |
11161216 11385574 16382100 |
| RefSeq identity: |
NM_017672 |
| Classification: |
Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000172449 |