| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MARK2 (EMK) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the MARK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This MARK2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q7KZI7 |
| Purity: |
Antigen affinity |
| Description: |
By this basic mechanism, The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains, With more than 500 gene products, and differentiation, apoptosis, cell cycle progression, cytoskeletal rearrangement and cell movement, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, the protein kinase family is one of the largest families of proteins in eukaryotes, transcription, Protein kinases are enzymes that transfer a phosphate group from a phosphate donor |
| Immunogen: |
A portion of amino acids 600-630 from the human protein was used as the immunogen for this MARK2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MARK2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MARK2 (EMK) |
| Short name: |
MARK2 Antibody (EMK) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
mitogen-stimulated protein kinase/microtubule affinity-regulating kinase 2 (Antibody to) (EMK) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EMK-1 and EMK1 and PAR-1 and Par-1b and Par1b, MARK2 and IDBG-52754 and ENSG00000072518 and 2011, MARK2 and IDBG-643848 and ENSBTAG00000007825 and 535197, Mark2 and IDBG-138576 and ENSMUSG00000024969 and 13728, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0001764 and neuron migration and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005884 and actin filament and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0008289 and lipid binding and molecular function this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008289 : lipid binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008289 : lipid binding, this GO :0016772 : transferase activity, this GO :0044822 : poly(A) RNA binding, this GO :0050321 : tau-protein kinase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822 : poly(A) RNA binding and also this GO :0050321 : tau-protein kinase activity, transferring phosphorus-containing groups and molecular function this GO :0030010 and establishment of cell polarity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045180 and basal cortex and cellular component this GO :0045197 and establishment or maintenance of epithelial cell apical/basal polarity and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050321 and tau-protein kinase activity and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0051493 and regulation of cytoskeleton organization and biological process this GO :0097427 and microtubule bundle and cellular component, MAP/microtubule affinity-regulating kinase 2 |
| Identity: |
3332 |
| Gene: |
MARK2 |
More about : MARK2 |
| Long gene name: |
microtubule affinity regulating kinase 2 |
| Synonyms gene: |
EMK1 |
| Synonyms gene name: |
ELKL motif kinase MAP/microtubule affinity-regulating kinase 2 |
| Synonyms: |
PAR-1 Par1b PAR-1B |
| Synonyms name: |
ELKL motif kinase 1 serine/threonine kinase protein-serine/threonine kinase Ser/Thr protein kinase PAR-1B |
| Locus: |
11q13, 1 |
| Discovery year: |
1994-12-08 |
| GenBank acession: |
BC008771 |
| Entrez gene record: |
2011 |
| Pubmed identfication: |
9730619 10516437 |
| RefSeq identity: |
NM_017490 |
| Havana BLAST/BLAT: |
OTTHUMG00000160504 |