MYLK3 Antibody

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Catalog number: F40165-0.4ML
Price: 406 €
Supplier: NJS poly
Product name: MYLK3 Antibody
Quantity: 0.4 ml
Other quantities: 0.08 ml 199€ 0.1ml 263€
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Category: Antibody
Concentration: pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form: Purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: MYLK3
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: ELISA, WB, IHC
Recommended dilutions: IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
Notes: Titration of the MYLK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use: This MYLK3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: Q32MK0
Purity: Purified
Description: In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells, It is a central determinant in the development of vascular permeability and tissue edema formation, MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis, MLCK is probably down-regulated by phosphorylation, Non-muscle isoform 2 is the dominant splice variant expressed in various tissues, Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific, The Telokin isoform, The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains, a member of the Ser/Thr protein kinase family, an event that facilitates myosin interaction with actin filaments, has been found in a wide variety of adult and fetal tissues, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), which binds calmodulin, MLCK/MYLK3
Immunogen: A portion of amino acids 40-69 from the human protein was used as the immunogen for this MYLK3 antibody
Storage: Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MYLK3 antibody and store frozen at -20 deg
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: MYLK3
Short name: MYLK3 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: MYLK3 (Antibody to)
Alternative technique: antibodies
Identity: 29826
Gene: MYLK3 | More about : MYLK3
Long gene name: myosin light chain kinase 3
Synonyms: caMLCK MLCK
Synonyms name: MLC kinase
Locus: 16q11, 2
Discovery year: 2008-01-23
GenBank acession: AJ247087
Entrez gene record: 91807
Pubmed identfication: 17885681
RefSeq identity: NM_182493
Havana BLAST/BLAT: OTTHUMG00000132543

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