| Alternative name 1: |
Clone: ICR10, IH/WB/IP, Rat Mab anti-Human, frozen, Epidermal Growth Factor Receptor (EGFR) |
| Alternative name 2: |
Clone: ICR10, IH/WB/IP, Rat Mab antibody-Human, frozen, Epidermal Growth Factor Receptor (EGFR) |
| Alternative name 3: |
Clone: ICR10, IH/WB/IP, Rattus norvegicus Mab antibody-Homo sapiens, frozen, Epidermal Growth Factor Receptor (EGFR) |
| Alternative name 4: |
anti-Epidermal Growth Factor Receptor EGFR Clone: ICR10 |
| Alternative name 5: |
Epidermal Growth Factor Receptor EGFR Clone: ICR10 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
IH/ /IP, Monoclonal frozen, Epidermal Growth Factor Receptor (EGFR) ICR10 |
| Short name: |
IH/ /IP, Mouse Monoclonal antibody- frozen, Epidermal Growth Factor Receptor (EGFR) Clone: ICR10 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, frozen |
| Host: |
Rat |
| Species: |
Humans, Mouses, Rats, Human |
| Alternative name: |
-25°, IH/Western Blot/IP, Rat Mouse monoclonal (Antibody to)-H, clonality: ICR10, sapiens, C frozen, Epidermal Growth Factor Receptor (epidermal growth factor receptor) |
| Alternative technique: |
murine |
| Alternative to gene target: |
EGFR and IDBG-16933 and ENSG00000146648 and 1956, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217, ERBB and ERBB1 and HER1 and mENA and PIG61, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, glutamatergic and biological process this GO :0060571 and morphogenesis of an epithelial fold and biological process this GO :0070141 and response to UV-A and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070435 and Shc-EGFR complex and cellular component this GO :0071230 and cellular response to amino acid stimulus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071364 and cellular response to epidermal growth factor stimulus and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001503 and ossification and biological process this GO :0001889 and liver development and biological process this GO :0001892 and embryonic placenta development and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001942 and hair follicle development and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005006 and epidermal growth factor-activated receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006412 and translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0006970 and response to osmotic stress and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007411 and axon guidance and biological process this GO :0007435 and salivary gland morphogenesis and biological process this GO :0007611 and learning or memory and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010960 and magnesium ion homeostasis and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016101 and diterpenoid metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016772 and transferase activity, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0004672 : protein kinase activity and also this GO :0004709 : MAP kinase kinase kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005006 : epidermal growth factor-activated receptor activity and also this GO :0005102 : receptor binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0004672 : protein kinase activity, this GO :0004709 : MAP kinase kinase kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005006 : epidermal growth factor-activated receptor activity, this GO :0005102 : receptor binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030235 : nitric-oxide synthase regulator activity, this GO :0042802 : identical protein binding, this GO :0046982 : protein heterodimerization activity, this GO :0048408 : epidermal growth factor binding, this GO :0051015 : actin filament binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030235 : nitric-oxide synthase regulator activity and also this GO :0042802 : identical protein binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0048408 : epidermal growth factor binding and also this GO :0051015 : actin filament binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019694 and alkanesulfonate metabolic process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021795 and cerebral cortex cell migration and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030122 and AP-2 adaptor complex and cellular component this GO :0030139 and endocytic vesicle and cellular component this GO :0030235 and nitric-oxide synthase regulator activity and molecular function this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031659 and positive regulation of cyclin-dependent protein kinase activity involved in G1/S and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0032355 and response to estradiol and biological process this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033590 and response to cobalamin and biological process this GO :0033594 and response to hydroxyisoflavone and biological process this GO :0033993 and response to lipid and biological process this GO :0035413 and positive regulation of catenin import into nucleus and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035690 and cellular response to drug and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042177 and negative regulation of protein catabolic process and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042698 and ovulation cycle and biological process this GO :0042743 and hydrogen peroxide metabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043006 and activation of phospholipase A2 activity by calcium-mediated signaling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043586 and tongue development and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048143 and astrocyte activation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048408 and epidermal growth factor binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048546 and digestive tract morphogenesis and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051205 and protein insertion into membrane and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051968 and positive regulation of synaptic transmission, epidermal growth factor receptor |
| Identity: |
3236 |
| Gene: |
EGFR |
More about : EGFR |
| Long gene name: |
epidermal growth factor receptor |
| Synonyms gene: |
ERBB |
| Synonyms gene name: |
epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) |
| Synonyms: |
ERBB1 |
| Synonyms name: |
erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian) erb-b2 receptor tyrosine kinase 1 |
| Locus: |
7p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
1956 |
| Pubmed identfication: |
1505215 |
| RefSeq identity: |
NM_005228 |
| Classification: |
Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000023661 |
| Locus Specific Databases: |
LRG_304 |