Phospho-CRK Antibody (pS41)

Catalog number:	F40128-0.4ML Buy Now
Price:	348 €
Supplier:	MBS Polyclonals
Product name:	Phospho-CRK Antibody (pS41)
Quantity:	0.12 ml
Related search:	antibody phosphocrk crk gene deg identity need

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Category:	Antibody
Concentration:	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form:	Antigen affinity purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	Phospho-CRK (pS41)
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications:	ELISA, DB
Recommended dilutions:	Dot blot: 1:500
Notes:	Titration of the phospho-CRK antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use:	This phospho-CRK antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	P46108
Purity:	Antigen affinity
Description:	It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins
Immunogen:	This phospho-CRK antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS41 of human CRK
Storage:	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-CRK antibody and store frozen at -20 deg
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	Phospho-CRK (pS41)
Short name:	Phospho-CRK Antibody (pS41)
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	phosphorilated-CRK (Antibody to) (pS41)
Alternative technique:	antibodies
Identity:	2362
Gene:	CRK | More about : CRK
Long gene name:	CRK proto-oncogene, adaptor protein
Synonyms gene name:	v-crk avian sarcoma virus CT10 oncogene homolog
Locus:	17p13, 3
Discovery year:	1992-12-07
GenBank acession:	D10656
Entrez gene record:	1398
Pubmed identfication:	1690891
RefSeq identity:	NM_016823
Classification:	SH2 domain containing
Havana BLAST/BLAT:	OTTHUMG00000090317

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