| Category: |
Antibody |
| Concentration: |
09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Endoplasmic Reticulum Amyloid Binding Protein (ERAB) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB, IHC |
| Recommended dilutions: |
IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes: |
Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This ERAB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q6IBS9 |
| Purity: |
Antigen affinity |
| Description: |
ERAB appears to trigger cell stress induced by the amyloid peptide, In an amyloid beta-abundant environment, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols, unique among this family, Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases |
| Immunogen: |
A portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ERAB antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Endoplasmic Reticulum Amyloid Binding Protein (ERAB) |
| Short name: |
Endoplasmic Reticulum Amyloid Binding Protein Antibody (ERAB) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Endoplasmic Reticulum Amyloid Binding Protein (Antibody to) (ERAB) |
| Alternative technique: |
antibodies |
| Identity: |
4800 |
| Gene: |
HSD17B10 |
More about : HSD17B10 |
| Long gene name: |
hydroxysteroid 17-beta dehydrogenase 10 |
| Synonyms gene: |
HADH2 MRXS10 |
| Synonyms gene name: |
X-linked, hydroxyacyl-Coenzyme A dehydrogenase, hydroxyacyl-Coenzyme A dehydrogenase, syndromic 10 hydroxysteroid (17-beta) dehydrogenase 10 , type II, type II mental retardation |
| Synonyms: |
ERAB MHBD 17b-HSD10 ABAD SDR5C1 MRPP2 CAMR |
| Synonyms name: |
member 1 mitochondrial RNase P subunit 2 , type 10 17b-HSD type 10 17beta-hydroxysteroid dehydrogenase AB-binding alcohol dehydrogenase short chain dehydrogenase/reductase family 5C |
| Locus: |
Xp11, 22 |
| Discovery year: |
1997-04-25 |
| GenBank acession: |
U96132 |
| Entrez gene record: |
3028 |
| Pubmed identfication: |
9338779 16899120 19027726 18984158 17236142 |
| RefSeq identity: |
NM_004493 |
| Classification: |
X-linked mental retardation Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000021612 |
| Locus Specific Databases: |
Mental Retardation database LRG_450 |