| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MDS1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the MDS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This MDS1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13465 |
| Purity: |
Antigen affinity |
| Description: |
EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes, In cells with translocation t (3, MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1, additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame, 21), MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped |
| Immunogen: |
A portion of amino acids 81-109 from the human protein was used as the immunogen for this MDS1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the MDS1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MDS1 |
| Short name: |
MDS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MDS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3498 |
| Gene: |
MECOM |
More about : MECOM |
| Long gene name: |
MDS1 and EVI1 complex locus |
| Synonyms gene: |
MDS1 EVI1 |
| Synonyms gene name: |
myelodysplasia syndrome 1 ecotropic viral integration site 1 |
| Synonyms: |
MDS1-EVI1 PRDM3 KMT8E |
| Synonyms name: |
PR domain 3 |
| Locus: |
3q26, 2 |
| Discovery year: |
1990-07-10 |
| GenBank acession: |
S82592 AF164154 |
| Entrez gene record: |
2122 |
| Pubmed identfication: |
2115646 8171026 8643684 |
| RefSeq identity: |
NM_005241 NM_004991 |
| Classification: |
Lysine methyltransferases Zinc fingers C2H2-type PR/SET domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000158596 |