| Gene info: |
During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation, In synergy with IL15 and IL18 stimulates interferon &, Induces the production of IgG(1) and IgG(3) in B-cells (By similarity), May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15, May promote the transition between innate and adaptive immunity, May regulate proliferation of mature B- and T-cells in response to activating stimuli, production in T-cells and NK cells, #947, <, /b>, : Cytokine with immunoregulatory activity, FUNCTION<, b> |
| Gene names: |
IL-21, Interleukin21, Za11, Interleukin-21 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
33-111 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
may also work for ICC and IHC, Interleukin-21 antibody can be used for the detection of Interleukin-21 by ELISA and Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, IL21 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
46575632 |
| Ncbi nr: |
1, AAH69124 |
| KDa: |
17, 9 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
59067 |
| GENE symbol: |
IL21 |
| Antigene name: |
interleukin 21 |
| Source: |
Homo sapiens |
| Protein nr: |
Q9HBE4 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IL21 |
| Short name: |
anti-IL21 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-interleukin 21 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, IL21 and IDBG-36977 and ENSG00000138684 and 59067, IL21 and IDBG-630309 and ENSBTAG00000012368 and 378475, Il21 and IDBG-140267 and ENSMUSG00000027718 and 60505, interleukin-2 receptor binding, this GO :0002729 and positive regulation of natural killer cell cytokine production and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005126 and cytokine receptor binding and molecular function this GO :0005134 and interleukin-2 receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032825 and positive regulation of natural killer cell differentiation and biological process this GO :0034105 and positive regulation of tissue remodeling and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0048469 and cell maturation and biological process this GO :0050729 and positive regulation of inflammatory response and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005126 : cytokine receptor binding and also this GO :0005134 : interleukin-2 receptor binding, this GO :0005126 : cytokine receptor binding, this GO :0005134 : interleukin-2 receptor binding, interleukin 21 |
| Identity: |
6005 |
| Gene: |
IL21 |
More about : IL21 |
| Long gene name: |
interleukin 21 |
| Synonyms: |
Za11 IL-21 |
| Locus: |
4q27 |
| Discovery year: |
2000-03-29 |
| GenBank acession: |
AF254069 |
| Entrez gene record: |
59067 |
| Pubmed identfication: |
11081504 17947662 |
| RefSeq identity: |
NM_021803 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000133073 |