| Gene info: |
In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators, The protein encoded by this gene is a member of the STAT family of transcription factors |
| Gene names: |
SLEB11, Signal transducer and activator of transcription 4 variant, Signal transducer and activator of transcription 4 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
51-230 |
| Immuno application: |
Western Blot |
| Antibody advice: |
Signal transducer and activator of transcription 4 variant antibody can be used for the detection of Signal transducer and activator of transcription 4 variant by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, STAT4 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
4507255 |
| Ncbi nr: |
1, NP_003142 |
| KDa: |
37, 6 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
6775 |
| GENE symbol: |
STAT4 |
| Antigene name: |
signal transducer and activator of transcription 4 |
| Source: |
Homo sapiens |
| Protein nr: |
Q14765 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
STAT4 |
| Short name: |
anti-STAT4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-signal transducer and activator on transcription 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0008283 and cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071310 and cellular response to organic substance and biological process, SLEB11, STAT4 and IDBG-642767 and ENSBTAG00000046699 and, STAT4 and IDBG-77625 and ENSG00000138378 and 6775, Stat4 and IDBG-152917 and ENSMUSG00000062939 and 20849, nuclei, sequence-specific DNA binding, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0043565 : sequence-specific DNA binding, signal transducer and activator of transcription 4 |
| Identity: |
11365 |
| Gene: |
STAT4 |
More about : STAT4 |
| Long gene name: |
signal transducer and activator of transcription 4 |
| Locus: |
2q32, 2-q32, 3 |
| Discovery year: |
1995-11-08 |
| Entrez gene record: |
6775 |
| Pubmed identfication: |
8007943 8700208 |
| RefSeq identity: |
NM_003151 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132700 |