| Gene info: |
IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, It is also involved in neutrophil activation, It is released from several cell types in response to an inflammatory stimulus, and T-cells, basophils, but not monocytes, respectively, <, /b>, : IL-8 is a chemotactic factor that attracts neutrophils, FUNCTION<, b> |
| Gene names: |
C-X-C motif chemokine 8, CXCL8, Emoctaki, GCP-1, GCP1, Granulocyte chemotactic protein 1, IL-8, Interleukin-8, Interleukin8, LECT, LUCT, LYNAP, MDNCF, MONAP, Monocyte derived neutrophil-activating peptide, Monocyte-derived neutrophil chemotactic factor, NAF, NAP-1, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor, CXCL8 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
28-99 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
may also work for ICC and IHC, Interleukin-8 antibody can be used for the detection of Interleukin-8 by ELISA and Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, IL8 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
124359 |
| Ncbi nr: |
P10145 |
| KDa: |
1 kDa (calculated), 11 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3576 |
| GENE symbol: |
IL8 |
| Antigene name: |
interleukin 8 |
| Source: |
Homo sapiens |
| Protein nr: |
P10145 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene: |
CXCL8 |
More about : CXCL8 |
| Gene target: |
IL8 |
| Short name: |
anti-IL8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-interleukin 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828, chemokine activity, this GO :0001525 and angiogenesis and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0005153 and interleukin-8 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031623 and receptor internalization and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042119 and neutrophil activation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045087 and innate immune response and biological process this GO :0045091 and regulation of retroviral genome replication and biological process this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0048566 and embryonic digestive tract development and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0090023 and positive regulation of neutrophil chemotaxis and biological process, this GO :0005153 : interleukin-8 receptor binding, this GO :0005153 : interleukin-8 receptor binding and also this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity, this GO :0005515 : protein binding, this GO :0008009 : chemokine activity, interleukin 8 |
| Identity: |
6025 |
| Long gene name: |
C-X-C motif chemokine ligand 8 |
| Synonyms gene: |
IL8 |
| Synonyms gene name: |
interleukin 8 chemokine (C-X-C motif) ligand 8 |
| Synonyms: |
SCYB8 LUCT LECT MDNCF TSG-1 IL-8 NAP-1 3-10C MONAP AMCF-I LYNAP NAF b-ENAP GCP-1 K60 GCP1 NAP1 |
| Synonyms name: |
neutrophil-activating peptide 1 granulocyte chemotactic protein 1 monocyte-derived neutrophil chemotactic factor lung giant cell carcinoma-derived chemotactic protein tumor necrosis factor-induced gene 1 monocyte-derived neutrophil-activating peptide lymphocyte derived neutrophil activating peptide beta endothelial cell-derived neutrophil activating peptide alveolar macrophage chemotactic factor I |
| Locus: |
4q13, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
Y00787 |
| Entrez gene record: |
3576 |
| Pubmed identfication: |
1427896 11178128 |
| RefSeq identity: |
NM_000584 |
| Classification: |
Endogenous ligands Chemokine ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000151316 |