| Gene info: |
The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity, This cytokine is an important mediator of the inflammatory response, This cytokine is produced by activated macrophages as a proprotein, This protein and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2, and apoptosis, and is involved in a variety of cellular activities, differentiation, including cell proliferation, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE), The protein encoded by this gene is a member of the interleukin 1 cytokine family |
| Gene names: |
Catabolin, IL-1, IL-1 beta, IL1-BETA, IL1F2, Interleukin 1 b, Interleukin-1 beta, IL1F2 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
118-269 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
antibody can be used for the detection of Interleukin 1 &, by ELISA and Western Blot, may also work for ICC and IHC, #946, #946, Interleukin 1 & |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, IL1b antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
10835145 |
| Ncbi nr: |
1, NP_000567 |
| KDa: |
17, 4 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3553 |
| GENE symbol: |
IL1B |
| Antigene name: |
beta, interleukin 1 |
| Source: |
Homo sapiens |
| Protein nr: |
P01584 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IL1b |
| Short name: |
anti-IL1b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
beta (Antibody to), antibody to-interleukin 1 |
| Alternative technique: |
antibodies |
| Identity: |
5992 |
| Gene: |
IL1B |
More about : IL1B |
| Long gene name: |
interleukin 1 beta |
| Synonyms: |
IL1F2 IL-1B IL1-BETA |
| Locus: |
2q14, 1 |
| Discovery year: |
1989-03-31 |
| GenBank acession: |
M15330 |
| Entrez gene record: |
3553 |
| Pubmed identfication: |
2954882 2989698 |
| RefSeq identity: |
NM_000576 |
| Classification: |
Endogenous ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000131344 |