| Gene info: |
<, <, <, <, A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi, Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP), Ras family, <, /b>, /b>, /b>, /b>, /b>, : Alternate between an inactive form bound to GDP and an active form bound to GTP, : Belongs to the small GTPase superfamily, : Defects in HRAS are also the cause of oral squamous cell carcinomas (OSCC), : Palmitoylated by the ZDHHC9-GOLGA7 complex, : Ras proteins bind GDP/GTP and possess intrinsic GTPase activity, DISEASE<, ENZYME REGULATION<, FUNCTION<, PTM<, SIMILARITY<, b>, b>, b>, b>, b> |
| Gene names: |
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, GTPase HRas, H-RASIDX, H-Ras-1, HAMSV, HRAS1, K-RAS, N-RAS, RASH1, Transforming protein p21, c-H-ras, HRAS1 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
116-189 |
| Immuno application: |
Western Blot |
| Antibody advice: |
GTPase HRas antibody can be used for the detection of GTPase HRas by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, HRAS antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Rat, Mouse |
| Omim nr: |
4885425 |
| Ncbi nr: |
1, NP_005334 |
| KDa: |
21, 3 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3265 |
| GENE symbol: |
HRAS |
| Antigene name: |
Harvey rat sarcoma viral oncogene homolog |
| Source: |
Homo sapiens |
| Protein nr: |
P01112 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
HRAS |
| Short name: |
anti-HRAS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-v-Ha-ras Harvey rat sarcoma viral oncogene homolog (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-BAS/HAS and C-H-RAS and C-HA-RAS1 and CTLO and H-RASIDX and HAMSV and HRAS1 and p21ras and RASH1, GABAergic and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0034259 and negative regulation of Rho GTPase activity and biological process this GO :0035022 and positive regulation of Rac protein signal transduction and biological process this GO :0035176 and social behavior and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046579 and positive regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0090303 and positive regulation of wound healing and biological process this GO :0090398 and cellular senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900029 and positive regulation of ruffle assembly and biological process this GO :2000251 and positive regulation of actin cytoskeleton reorganization and biological process this GO :2000630 and positive regulation of miRNA metabolic process and biological process, HRAS and IDBG-16878 and ENSG00000174775 and 3265, HRAS and IDBG-645593 and ENSBTAG00000046644 and 100298939, Hras1 and IDBG-212024 and ENSMUSG00000025499 and 15461, ferrous iron transmembrane transporter activity, nuclei, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006935 and chemotaxis and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007411 and axon guidance and biological process this GO :0007569 and cell aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008542 and visual learning and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0015031 and protein transport and biological process this GO :0015093 and ferrous iron transmembrane transporter activity and molecular function this GO :0015684 and ferrous iron transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0032228 and regulation of synaptic transmission, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0015093 : ferrous iron transmembrane transporter activity, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, this GO :0008022 : protein C-terminus binding, this GO :0015093 : ferrous iron transmembrane transporter activity, v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
| Identity: |
5173 |
| Gene: |
HRAS |
More about : HRAS |
| Long gene name: |
GTPase , HRas proto-oncogene |
| Synonyms gene: |
HRAS1 |
| Synonyms gene name: |
v-Ha-ras Harvey rat sarcoma viral oncogene homolog Harvey rat sarcoma viral oncogene homolog |
| Locus: |
11p15, 5 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AJ437024 |
| Entrez gene record: |
3265 |
| RefSeq identity: |
NM_176795 |
| Classification: |
RAS type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000131919 |
| Locus Specific Databases: |
LRG_506 |