| Gene info: |
Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol, which then accelerates apoptosis by activating other caspases, <, /b>, : Plays a role in apoptosis, FUNCTION<, b> |
| Gene names: |
Cytochrome c, CYC |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Immunoaffinity Purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
1-104 |
| Immuno application: |
Western Blot |
| Antibody advice: |
CYCS antibody can be used for the detection of Cytochrome c by Western Blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, CYCS antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
11128019 |
| Ncbi nr: |
1, NP_061820 |
| KDa: |
11, 6 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
54205 |
| GENE symbol: |
CYCS |
| Antigene name: |
somatic, cytochrome c |
| Source: |
Homo sapiens |
| Protein nr: |
P99999 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
CYCS |
| Short name: |
anti-CYCS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
somatic (Antibody to), antibody to-cytochrome c |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CYCS and IDBG-10008 and ENSG00000172115 and 54205, electron transporter, nuclei, somatic, this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005829 and cytosol and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006915 and apoptotic process and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0016311 and dephosphorylation and biological process this GO :0020037 and heme binding and molecular function this GO :0022904 and respiratory electron transport chain and biological process this GO :0044237 and cellular metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045155 and electron transporter, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0005506 : iron ion binding and also this GO :0005515 : protein binding and also this GO :0009055 : electron carrier activity and also this GO :0020037 : heme binding and also this GO :0045155 : electron transporter, this GO :0005506 : iron ion binding, this GO :0005515 : protein binding, this GO :0009055 : electron carrier activity, this GO :0020037 : heme binding, this GO :0045155 : electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity and molecular function this GO :0045333 and cellular respiration and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070469 and respiratory chain and cellular component this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, cytochrome c |
| Identity: |
19986 |
| Gene: |
CYCS |
More about : CYCS |
| Long gene name: |
cytochrome c, somatic |
| Synonyms: |
HCS CYC |
| Locus: |
7p15, 3 |
| Discovery year: |
2002-12-16 |
| GenBank acession: |
M22877 |
| Entrez gene record: |
54205 |
| Pubmed identfication: |
11790791 |
| Havana BLAST/BLAT: |
OTTHUMG00000128495 |
| Locus Specific Databases: |
LRG_876 |