| Gene info: |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development, Each of these proteins, Human proteins MECP2, In contrast to other MBD family members, MBD1, MBD1 and MBD2 can also repress transcription from methylated gene promoters, MBD2, MBD3, MECP2, MECP2 gene mutations are the cause of some cases of Rett syndrome, MECP2 is X-linked and subject to X inactivation, MECP2 is dispensible in stem cells, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD), but is essential for embryonic development, is capable of binding specifically to methylated DNA, with the exception of MBD3, Methyl CpG binding protein 2 (Rett syndrome) |
| Gene names: |
AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, Methyl-CpG-binding protein 2MeCp-2 protein |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Antigen affinity-purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
170-486 |
| Immuno application: |
Western Blot |
| Antibody advice: |
may also work for IHC and ICC, MeCP2 antibody can be used for the detection of MeCP2 by Western blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, MECP2 antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
4826830 |
| Ncbi nr: |
1, NP_004983 |
| KDa: |
4 kDa (calculated), 52 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
4204 |
| GENE symbol: |
MECP2 |
| Antigene name: |
methyl CpG binding protein 2 (Rett syndrome) |
| Source: |
Homo sapiens |
| Protein nr: |
P51608 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
MECP2 |
| Short name: |
anti-MECP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-MECP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6990 |
| Gene: |
MECP2 |
More about : MECP2 |
| Long gene name: |
methyl-CpG binding protein 2 |
| Synonyms gene: |
RTT MRX16 MRX79 |
| Synonyms gene name: |
X-linked 16 mental retardation, X-linked 79 Rett syndrome methyl CpG binding protein 2 (Rett syndrome) methyl CpG binding protein 2 , mental retardation |
| Locus: |
Xq28 |
| Discovery year: |
1996-09-03 |
| GenBank acession: |
AF158180 |
| Entrez gene record: |
4204 |
| Pubmed identfication: |
1606614 10508514 |
| RefSeq identity: |
NM_004992 |
| Classification: |
X-linked mental retardation Methyl-CpG binding domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024229 |
| Locus Specific Databases: |
RettBASE Mental Retardation database LRG_764 |