| Gene info: |
Leptin, M, Mice with mutations of the ob gene have been found to be obese and diabetic and to have reduced activity, a product of the Obese (ob) gene, and body temperature, is a ligand for the OB receptor (OC-R), leptin (murine obesity homolog), metabolism, obesity, 000, Leptin, W: 16 |
| Gene names: |
Leptin, OBS, Obese protein, OB |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Antigen affinity-purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
Full-length |
| Immuno application: |
Western Blot |
| Antibody advice: |
ELISA, may also work for IHC and ICC, Leptin antibody can be used for the detection of Leptin by Western blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, LEP antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Bovine, Mouse, Rat, Human |
| Omim nr: |
4557715 |
| Ncbi nr: |
1, NP_000221 |
| KDa: |
18, 6 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3952 |
| GENE symbol: |
LEP |
| Antigene name: |
leptin |
| Source: |
Homo sapiens |
| Protein nr: |
P41159 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
LEP |
| Short name: |
anti-LEP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-leptin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, LEP and IDBG-39587 and ENSG00000174697 and 3952, LEPD and OB and OBS, Lep and IDBG-130781 and ENSMUSG00000059201 and 16846, OBESE and IDBG-635003 and ENSBTAG00000014911 and 280836, peptide hormone receptor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001542 and ovulation from ovarian follicle and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0001890 and placenta development and biological process this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0002021 and response to dietary excess and biological process this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006111 and regulation of gluconeogenesis and biological process this GO :0006112 and energy reserve metabolic process and biological process this GO :0006114 and glycerol biosynthetic process and biological process this GO :0006629 and lipid metabolic process and biological process this GO :0006635 and fatty acid beta-oxidation and biological process this GO :0007165 and signal transduction and biological process this GO :0007260 and tyrosine phosphorylation of STAT protein and biological process this GO :0007565 and female pregnancy and biological process this GO :0007584 and response to nutrient and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008206 and bile acid metabolic process and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008343 and adult feeding behavior and biological process this GO :0009062 and fatty acid catabolic process and biological process this GO :0009892 and negative regulation of metabolic process and biological process this GO :0019222 and regulation of metabolic process and biological process this GO :0021954 and central nervous system neuron development and biological process this GO :0030073 and insulin secretion and biological process this GO :0030300 and regulation of intestinal cholesterol absorption and biological process this GO :0032099 and negative regulation of appetite and biological process this GO :0032868 and response to insulin and biological process this GO :0033197 and response to vitamin E and biological process this GO :0033210 and leptin-mediated signaling pathway and biological process this GO :0033686 and positive regulation of luteinizing hormone secretion and biological process this GO :0035630 and bone mineralization involved in bone maturation and biological process this GO :0042307 and positive regulation of protein import into nucleus and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042755 and eating behavior and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043270 and positive regulation of ion transport and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045598 and regulation of fat cell differentiation and biological process this GO :0045639 and positive regulation of myeloid cell differentiation and biological process this GO :0045906 and negative regulation of vasoconstriction and biological process this GO :0046427 and positive regulation of JAK-STAT cascade and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0046881 and positive regulation of follicle-stimulating hormone secretion and biological process this GO :0048639 and positive regulation of developmental growth and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0050810 and regulation of steroid biosynthetic process and biological process this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0051428 and peptide hormone receptor binding and molecular function this GO :0060587 and regulation of lipoprotein lipid oxidation and biological process this GO :0060612 and adipose tissue development and biological process this GO :0061037 and negative regulation of cartilage development and biological process this GO :0070093 and negative regulation of gluca this GO n secretion and biological process this GO :0071298 and cellular response to L-ascorbic acid and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :2000366 and positive regulation of STAT protein import into nucleus and biological process this GO :2000486 and negative regulation of glutamine transport and biological process this GO :2000491 and positive regulation of hepatic stellate cell activation and biological process, this GO :0005179 : hormone activity, this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0051428 : peptide hormone receptor binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0051428 : peptide hormone receptor binding, leptin |
| Identity: |
6553 |
| Gene: |
LEP |
More about : LEP |
| Long gene name: |
leptin |
| Synonyms gene: |
OBS OB |
| Synonyms gene name: |
leptin (murine obesity homolog) leptin (obesity homolog, mouse) |
| Locus: |
7q32, 1 |
| Discovery year: |
1993-01-26 |
| Entrez gene record: |
3952 |
| Pubmed identfication: |
1686014 16932309 |
| Havana BLAST/BLAT: |
OTTHUMG00000157564 |