| Gene info: |
High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), This cytokine regulates the activities of NF-kB and mitogen-activated protein kinases, This protein is a proinflammatory cytokine produced by activated T cells, as well as enhance the production of nitric oxide (NO), cytotoxic T-lymphocyte-associated serine esterase 8, psoriasis and multiple sclerosis, Interleukin 17 |
| Gene names: |
IGIF, IL-18, IL-1g, IL1F4, Iboctadekin, Interleukin-18, IGIF |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Antigen affinity-purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
37-193 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Western blot, may also work for IHC and ICC, IL17 antibody can be used for the detection of IL-17 by ELISA |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, IL17A antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
4504653 |
| Ncbi nr: |
1, NP_001553 |
| KDa: |
17, 5 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
3606 |
| GENE symbol: |
IL18 |
| Antigene name: |
interleukin 18 (interferon-gamma-inducing factor) |
| Source: |
Homo sapiens |
| Protein nr: |
Q14116 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
IL17A |
| Short name: |
anti-IL17A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-interleukin 17A (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CTLA8 and IL-17 and IL-17A and IL17, Extracellular, IL17A and IDBG-632619 and ENSBTAG00000002150 and 282863, IL17A and IDBG-90504 and ENSG00000112115 and 3605, Il17a and IDBG-136575 and ENSMUSG00000025929 and 16171, cytokine activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006486 and protein glycosylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008219 and cell death and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0032747 and positive regulation of interleukin-23 production and biological process this GO :0045087 and innate immune response and biological process this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0072537 and fibroblast activation and biological process this GO :1900017 and positive regulation of cytokine production involved in inflammatory response and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity, interleukin 17A |
| Identity: |
5981 |
| Gene: |
IL17A |
More about : IL17A |
| Long gene name: |
interleukin 17A |
| Synonyms gene: |
CTLA8 IL17 |
| Synonyms gene name: |
interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) |
| Synonyms: |
IL-17A IL-17 |
| Synonyms name: |
cytotoxic T-lymphocyte-associated protein 8 |
| Locus: |
6p12, 2 |
| Discovery year: |
1993-10-25 |
| GenBank acession: |
U32659 |
| Entrez gene record: |
3605 |
| Pubmed identfication: |
8390535 |
| RefSeq identity: |
NM_002190 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000014840 |