| Gene info: |
B-, C1q associates with the proenzymes C1R and C1S to yield C1, C1q is composed of 18 polypeptide chains: six A-chains, Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis, Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region, The A-, and C-chains are arranged in the order A-C-B on chromosome 1, and six C-chains, six B-chains, the first component of the serum complement system, C1q |
| Gene names: |
Complement C1q subcomponent subunit A |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Antigen affinity-purified |
| Ab raised in: |
Chicken |
| Type: |
Polyclonal |
| Antigen: |
Human plasma C1q protein |
| Immuno application: |
ELISA |
| Antibody advice: |
ELISA, may also work for IHC and ICC, C1q antibody can be used for the detection of C1q by Western blot |
| Suspention, pH, azide: |
No preservatives added, Phosphate-Buffered Saline |
| Keep at: |
Antibodies should not be exposed to prolonged high temperatures, As with all antibodies care should be taken to avoid repeated freeze thaw cycles, Long term storage should be at -20 grades C, C1QA antibody can be stored at 4 grades C for short term (weeks) |
| Works with: |
Human |
| Omim nr: |
11038662 (B), 27363488 (C), 7705753 (A) |
| Ncbi nr: |
NP_000482, NP_758957, 1 (A), 1 (C), 2 (B), NP_057075 |
| KDa: |
26 kDa (calculated) |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
712 |
| GENE symbol: |
C1QA |
| Antigene name: |
A chain, q subcomponent, complement component 1 |
| Source: |
Homo sapiens |
| Protein nr: |
P02745 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
C1QA |
| Short name: |
anti-C1QA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
A chain (Antibody to), q subcomponent, antibody to-complement component 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
A chain, C1QA and IDBG-645509 and ENSBTAG00000007153 and 534961, C1QA and IDBG-93718 and ENSG00000173372 and 712, C1qa and IDBG-198277 and ENSMUSG00000036887 and 12259, Extracellular, classical pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, protein binding, q subcomponent, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005602 and complement component C1 complex and cellular component this GO :0006956 and complement activation and biological process this GO :0006958 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding, complement component 1 |
| Identity: |
1241 |
| Gene: |
C1QA |
More about : C1QA |
| Long gene name: |
complement C1q A chain |
| Synonyms gene name: |
A chain complement C1q chain A , alpha polypeptide complement component 1, complement component 1, q subcomponent, q subcomponent |
| Locus: |
1p36, 12 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF135157 |
| Entrez gene record: |
712 |
| Pubmed identfication: |
1537612 |
| RefSeq identity: |
NM_015991 |
| Classification: |
Complement system |
| Havana BLAST/BLAT: |
OTTHUMG00000002893 |
| Locus Specific Databases: |
C1QAbase: Mutation registry for C1qA deficiency LRG_22 |