| Gene info: |
In addition to its role in plasticity, Phosphorylation of this site is thought to regulate synaptic vesicle function, Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I, The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation, This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release, Thus synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis, the expression of synapsin I is a precise indicator of synapse formation, Synapsin I plays a key role in synaptic plasticity in brain |
| Gene names: |
Synapsin I |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Affinity Purified |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Spicific to: |
Synapsin antibody is specific for Synapsin I phosphorylated at Ser603 |
| Antigen: |
Synapsin (Ser603) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phosphorylated Ser609 of Rat Synapsin I |
| Immuno application: |
Western Blot |
| Antibody advice: |
Applications include Dot Blots (DB) and Western Blots (WB), Suitability for Immunohistochemistry (IHC) has not yet been determined, When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB, Immunolabeling of the 78k Synapsin I doublet in a Western blot of rat brain homogenate is blocked by the phosphopeptide used as antigen but not by the corresponding non-phosphopeptide |
| Suspention, pH, azide: |
100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5) |
| Keep at: |
Stable for one year, but shorter term storage at &ndash, 20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, 80 grades C is recommended, For long term storage &ndash |
| Works with: |
Rat |
| Omim nr: |
1351166 |
| Ncbi nr: |
P17599 |
| KDa: |
78 |
| Vial with antibody: |
in solution |
| NCBI GENE nr: |
281510 |
| GENE symbol: |
SYN1 |
| Antigene name: |
synapsin I |
| Source: |
Bos taurus |
| Protein nr: |
P17599 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Synapsin (phospho Ser603) |
| Short name: |
anti-Synapsin (phospho Ser603) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Synapsin (phosphorilated Ser603) (Antibody to) |
| Alternative technique: |
antibodies |