| Gene info: |
CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells, HIV 2, It binds to CCR1, It causes the release of histamine from basophils and activates eosinophils, It is T cell and macrophage specific, Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, and belongs to the intercrine beta (chemokine CC) family, and simian immunodeficiency virus (SIV), induced by mitogens, memory T helper cells and eosinophils, RANTES is a chemoattractant for blood monocytes |
| Gene names: |
C-C motif chemokine 5, CCL5, D17S136E, EoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP, Regulated upon activation normally T expressed and presumably secreted |
| Antibodie's label: |
unlabelled serum |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
5B3-D5 |
| Immunoglobulin: |
RANTES antibody was derived form BALB/c mice and belongs to the IgG2b isotype |
| Antigen: |
Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column |
| Immuno application: |
NELISAut, Western Blot, ELISA |
| Antibody advice: |
ELISA: In a sandwich ELISA (assuming 100 &, Used in conjunction with compatible secondary reagents the detection limit for recombinant hRANTES is 0, Western Blot: To detect hRANTES by Western Blot analysis this antibody can be used at a concentration of 0, a concentration of 2, a concentration of 5-7 ug/mL of this antibody is required, under non-reducing conditions, under reducing conditions and 0, #956, 0 ng/lane, 0 ug/mL, 0 ug/mL, 0 ug/mL of this antibody will detect at least 500 pg/mL of recombinant human RANTES when used with our biotinylated antigen affinity purified anti-human RANTES (XP-5257Bt) as the detection antibody at a concentration of approximately 0, 0-4, 25-0, 25-2, 5-1, 5-1, 50 ng/lane, L/well), Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of h-RANTES (100ng/mL) |
| Keep at: |
Reconstitute in sterile water to a concentration of 0, The antibody is stable for at least six weeks at 2-4 grades C when reconstituted, 0 mg/mL, 1 - 1, RANTES lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 grades C |
| Works with: |
Human |
| Omim nr: |
6175077 |
| Ncbi nr: |
P13501 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
6352 |
| GENE symbol: |
CCL5 |
| Antigene name: |
chemokine (C-C motif) ligand 5 |
| Source: |
Homo sapiens |
| Protein nr: |
P13501 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
RANTES [5B3-D5] |
| Short name: |
anti-RANTES Antibody [5B3-D5] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-RANTES (Antibody to) [5B3-D5] |
| Alternative technique: |
antibodies |
| Identity: |
10632 |
| Gene: |
CCL5 |
More about : CCL5 |
| Long gene name: |
C-C motif chemokine ligand 5 |
| Synonyms gene: |
D17S136E SCYA5 |
| Synonyms gene name: |
small inducible cytokine A5 (RANTES) chemokine (C-C motif) ligand 5 |
| Synonyms: |
RANTES SISd TCP228 MGC17164 |
| Synonyms name: |
T-cell specific protein p288 T-cell specific RANTES protein SIS-delta regulated upon activation, and presumably secreted beta-chemokine RANTES small inducible cytokine subfamily A (Cys-Cys), member 5 , normally T-expressed |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
AF043341 |
| Entrez gene record: |
6352 |
| Pubmed identfication: |
1691736 |
| RefSeq identity: |
NM_002985 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188396 |