| Gene info: |
IL10 and IL13, IL4 elicits many different biological responses, IL5, It is a ligand for Interleukin 4 receptor, STAT6, Th2 cells produce IL4, The Interleukin 4 receptor also binds to IL13, The first is regulating differentiation of naï, The second is regulating IgE and IgG1 production by B cells, Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, a signal transducer and activator of transcription, but has two dominant functions, has been shown to play a central role in mediating the immune regulatory signal of this cytokine, mast cells and basophils, which may contribute to many overlapping functions of this cytokine and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells, IL4 is a pleiotropic cytokine produced by activated T cells, ve CD4+ T cell to the Th2 type |
| Gene names: |
B-cell stimulatory factor 1, BCGF-1, BCGF1, BSF-1, BSF1, IL-4, Interleukin 4Interleukin-4 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
This IgG1k antibody was purified on a Protein A affinity column |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
1, 3_4F11-2G3 |
| Antigen: |
The monoclonal antibody was produced in BALB/c x ICR F1 mice using recombinant hIL-4 as the immunizing antigen |
| Immuno application: |
NELISAut, Western Blot, ELISA |
| Antibody advice: |
Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-4 is 0, Western Blot: To detect hIL-4 by Western Blot analysis this antibody can be used at a concentration of 0, a concentration of 0, a concentration of 6, under reducing or non-reducing conditions, #956, 0 ng/lane, 0 ng/mL), 0 ug/mL, 0 ug/mL of this antibody will detect at least 2000 pg/mL of recombinant human IL-4 when used with our biotinylated antigen affinity purified anti-human IL-4 (XP-5188Bt) as the detection antibody at a concentration of approximately 2, 0-4, 0-8, 20-0, 25-1, 5 ug/mL of this antibody is required, 5-1, 50 ug/mL, ELISA: In a sandwich ELISA (assuming 100 &, L/well), Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hIL-4 (1 |
| Keep at: |
Reconstitute in sterile water to a concentration of 0, The antibody is stable for at least six weeks at 2-4 grades C when reconstituted, 0 mg/mL, 1 - 1, IL-4 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 grades C |
| Works with: |
Human |
| Omim nr: |
124337 |
| Ncbi nr: |
P05112 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
3565 |
| GENE symbol: |
IL4 |
| Antigene name: |
interleukin 4 |
| Source: |
Homo sapiens |
| Protein nr: |
P05112 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
3_4F11-2G3], IL-4 [1 |
| Short name: |
3_4F11-2G3], anti-IL-4 Antibody [1 |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
3_4F11-2G3], antibody to-Interleukin-4 (Antibody to) [1 |
| Alternative technique: |
antibodies |
| Identity: |
6014 |
| Gene: |
IL4 |
More about : IL4 |
| Long gene name: |
interleukin 4 |
| Synonyms: |
BSF1 IL-4 BCGF1 BCGF-1 MGC79402 |
| Synonyms name: |
B_cell stimulatory factor 1 lymphocyte stimulatory factor 1 B cell growth factor 1 |
| Locus: |
5q31, 1 |
| Discovery year: |
1988-08-10 |
| GenBank acession: |
M23442 |
| Entrez gene record: |
3565 |
| Pubmed identfication: |
3016727 |
| RefSeq identity: |
NM_000589 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000059724 |