| Gene info: |
Alternatively spliced transcript variants of the gene have been reported, Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification, This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption, This protein specifically binds to its ligand, both of which are key extracellular regulators of osteoclast development, but their full length nature has not been determined, osteoprotegerin ligand (TNFSF11/OPGL), Osteoprotegerin (OPG) is a member of the TNF receptor superfamily |
| Gene names: |
OCIF, OPG, Osteoclastogenesis inhibitory factor, TR1, Tumor necrosis factor receptor superfamily member 11B, OPG |
| Antibodie's label: |
Biotin |
| Purity: |
Anti-hOPG specific antibody was purified by affinity chromatography and then biotinylated |
| Ab raised in: |
Rabbit |
| Type: |
Polyclonal |
| Antigen: |
98%) recombinant hOPG (human OPG), Produced from sera of rabbits pre-immunized with highly pure (> |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Sandwich: To detect hOPG by sandwich ELISA (using 100 &, This biotinylated polyclonal antibody, Used in conjunction with compatible secondary reagents, Used in conjunction with compatible secondary reagents the detection limit for recombinant hOPG is 1, Western Blot: To detect hOPG by Western Blot analysis this antibody can be used at a concentration of 0, allows the detection of at least 0, allows the detection of at least 0, in conjunction with our Polyclonal Anti-Human OPG (XP-5253) as a capture antibody, under either reducing or non-reducing conditions, #956, #956, 0 ng/lane, 0 ug/mL of this antibody is required, 1 - 0, 15 - 0, 2 - 0, 2 ng/well of recombinant hOPG, 2 ug/mL, 25 - 1, 30 ug/mL, 4 ng/well of recombinant hOPG, 5 - 3, ELISA: To detect hOPG by direct ELISA (using 100 &, L/well antibody solution) a concentration of 0, L/well antibody solution) this antibody can be used at a concentration of 0 |
| Keep at: |
Avoid repeated freeze-thaw cycles, Frozen aliquots are stable for at least 6 months when stored at -20 grades C, The reconstituted antibody is stable for at least two weeks at 2-8 grades C, Osteoprotegerin antibody is stable for at least 2 years from date of receipt at -20 grades C |
| Works with: |
Human |
| Omim nr: |
322510101 |
| Ncbi nr: |
O00300 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
4982 |
| GENE symbol: |
TNFRSF11B |
| Antigene name: |
member 11b, tumor necrosis factor receptor superfamily |
| Source: |
Homo sapiens |
| Protein nr: |
O00300 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Osteoprotegerin |
| Short name: |
anti-Osteoprotegerin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Osteoprotegerin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11909 |
| Gene: |
TNFRSF11B |
More about : TNFRSF11B |
| Long gene name: |
TNF receptor superfamily member 11b |
| Synonyms gene: |
OPG |
| Synonyms gene name: |
member 11b , osteoprotegerin tumor necrosis factor receptor superfamily |
| Synonyms: |
OCIF TR1 |
| Locus: |
8q24, 12 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
U94332 |
| Entrez gene record: |
4982 |
| Pubmed identfication: |
9108485 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000164969 |